delta-12 fatty acid desaturase

Organism:

Promoter:

Phenotypes:

The overexpression of NoD12 significantly altered fatty acid composition of total lipids and of individual lipid classes, such as a drastic increase in 18:2 proportion in phosphatidylcholine and in TAG was observed under nitrogen starvation.

• Yuval Kaye, Omer Grundman, Stefan Leu, Aliza Zarka, Boris Zorin, Shoshana Didi-Cohen, Inna Khozin-Goldberg, Sammy Boussiba. Metabolic engineering toward enhanced LC-PUFA biosynthesis in Nannochloropsis oceanica: Overexpression of endogenous Δ12 desaturase driven by stress-inducible promoter leads to enhanced deposition of polyunsaturated fatty acids in TAG. Algal Research,2015; 11:387-398.