NO22G01110, NO22G01110 (gene) Nannochloropsis oceanica

Overview
NameNO22G01110
Unique NameNO22G01110
Typegene
OrganismNannochloropsis oceanica (N. oceanica IMET1)
Sequence length795
Alignment locationchr22:341877..342671 -

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Properties
Property NameValue
DescriptionMethylmalonic aciduria and homocystinuria type D protein, mitochondrial
Mutants
Expression

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Alignments
The following features are aligned
Aligned FeatureFeature TypeAlignment Location
chr22genomechr22:341877..342671 -
Analyses
This gene is derived from or has results from the following analyses
Analysis NameDate Performed
PRJNA7699582024-08-13
GSE1786722023-12-15
PRJNA9336932023-10-26
PRJNA9434492023-07-19
GSE1499042020-10-10
NoIMET1_WT_HS2020-09-29
GSE1396152020-03-11
PRJNA2413822020-03-11
BLASTP analysis of N. oceanica IMET1 genes2019-07-11
InterPro analysis for N. oceanica IMET1 genes2019-07-11
GO annotation for IMET1v2 genes2019-07-10
PRJNA1821802019-04-25
Gene prediction for N. oceanica IMET12017-10-24
Annotated Terms
The following terms have been associated with this gene:
Vocabulary: Biological Process
TermDefinition
GO:0009235cobalamin metabolic process
GO:0009987cellular process
GO:0008152metabolic process
Vocabulary: INTERPRO
TermDefinition
IPR019362MMADHC
Homology
BLAST of NO22G01110 vs. NCBI_GenBank
Match: XP_005853627.1 (hypothetical protein NGA_0430401 [Nannochloropsis gaditana CCMP526] >EKU22738.1 hypothetical protein NGA_0430401 [Nannochloropsis gaditana CCMP526])

HSP 1 Score: 220.3 bits (560), Expect = 7.000e-54
Identity = 96/119 (80.67%), Postives = 109/119 (91.60%), Query Frame = 0
Query:  123 IQRSRVDTVRFGVDVEEEKDRCLEYFADFARPLCESLRSQGHWADFIDPCSGLPMMTPHCTRPYNEVAGFEHLLRYTTQNAGCCKILLHPRWGSSCYPATIFTTAPLENVQAAIKVAEK 242
            +Q+SR+DTVRFG +VEEEKDRCLE F  FARPLC+ LR QG WADFIDPCSGLPM+TPHCTRPY+EVAGFEHLLRY TQNAGCCKILLHPRWGSSCYPATIFTTAP++ V+AAI++ E+
Sbjct:    1 MQKSRLDTVRFGPEVEEEKDRCLERFVAFARPLCQGLRGQGFWADFIDPCSGLPMLTPHCTRPYSEVAGFEHLLRYKTQNAGCCKILLHPRWGSSCYPATIFTTAPVKTVRAAIQMLER 119          
BLAST of NO22G01110 vs. NCBI_GenBank
Match: GAQ88723.1 (hypothetical protein KFL_004540080 [Klebsormidium nitens])

HSP 1 Score: 160.6 bits (405), Expect = 6.600e-36
Identity = 74/125 (59.20%), Postives = 88/125 (70.40%), Query Frame = 0
Query:  117 LLILPTIQRSRVDTVRFGVDVEEEKDRCLEYFADFARPLCESLRSQGHWADFIDPCSGLPMMTPHCTRPYNEVAGFEHLLRYTTQNAGCCKILLHPRWGSSCYPATIFTTAPLENVQAAIKVAEK 242
            LLI+PT Q S VD VR G  +EEEKDR LE F DFA+ +CE L SQGHWAD++DP SGLPM+       Y+EV     LL YT QNAGCCK++LHP+WGSS YPAT+F  APLE V  AI   ++
Sbjct:   47 LLIIPTCQNSEVDLVRTGEVIEEEKDRLLEIFVDFAKQVCELLISQGHWADYLDPASGLPMIHKDTNTVYSEVDALSTLLHYTCQNAGCCKVILHPKWGSSVYPATLFAKAPLEVVLEAINKVDE 171          
BLAST of NO22G01110 vs. NCBI_GenBank
Match: XP_005851808.1 (hypothetical protein CHLNCDRAFT_133264 [Chlorella variabilis] >EFN59706.1 hypothetical protein CHLNCDRAFT_133264 [Chlorella variabilis])

HSP 1 Score: 154.5 bits (389), Expect = 4.700e-34
Identity = 69/123 (56.10%), Postives = 89/123 (72.36%), Query Frame = 0
Query:  117 LLILPTIQRSRVDTVRFGVDVEEEKDRCLEYFADFARPLCESLRSQGHWADFIDPCSGLPMMTPHCTRPYNEVAGFEHLLRYTTQNAGCCKILLHPRWGSSCYPATIFTTAPLENVQAAIKVA 240
            +L++PT Q +++D V+ G  VE+EKDR LE F +FA+ +CE L + GHWAD+IDPCSGLPM+       Y EV G   LL Y TQNAGCCKI+LHP+WGS+ YPA++F  APL  V AAI+ A
Sbjct:   41 MLVIPTCQHAQMDLVQMGQRVEDEKDRLLERFVEFAKTVCERLAALGHWADYIDPCSGLPMVHRATNAVYGEVEGLVTLLGYRTQNAGCCKIILHPKWGSNVYPASLFAKAPLAAVVAAIEEA 163          
BLAST of NO22G01110 vs. NCBI_GenBank
Match: PSC75053.1 (Methylmalonic aciduria and homocystinuria type D mitochondrial [Micractinium conductrix])

HSP 1 Score: 153.3 bits (386), Expect = 1.100e-33
Identity = 72/145 (49.66%), Postives = 93/145 (64.14%), Query Frame = 0
Query:  117 LLILPTIQRSRVDTVRFGVDVEEEKDRCLEYFADFARPLCESLRSQGHWADFIDPCSGLPMMTPHCTRPYNEVAGFEHLLRYTTQNAGCCKILLHPRWGSSCYPATIFTTAPLENVQAAIKVAEKGEAWREGGIGMRRVMEPAGV 262
            +L++PT Q ++VD V+ G  VE EKDR LE F +FA+ +CE L + GHWAD+IDPCSGLPM+       Y EV     LL Y TQNAGCCKI+LHP WGSS YPA++F  AP+         A +G+A  EG +G R +    G+
Sbjct:    1 MLVIPTCQHAQVDLVQMGEKVETEKDRLLERFVEFAKVVCERLAAAGHWADYIDPCSGLPMINRATNAVYGEVEALVTLLGYKTQNAGCCKIILHPCWGSSVYPASLFAKAPV--------AAAQGQAAEEGMVGRRLLQAAMGL 137          
BLAST of NO22G01110 vs. NCBI_GenBank
Match: XP_013893335.1 (hypothetical protein MNEG_13646 [Monoraphidium neglectum] >KIY94315.1 hypothetical protein MNEG_13646 [Monoraphidium neglectum])

HSP 1 Score: 152.5 bits (384), Expect = 1.800e-33
Identity = 68/125 (54.40%), Postives = 88/125 (70.40%), Query Frame = 0
Query:  117 LLILPTIQRSRVDTVRFGVDVEEEKDRCLEYFADFARPLCESLRSQGHWADFIDPCSGLPMMTPHCTRPYNEVAGFEHLLRYTTQNAGCCKILLHPRWGSSCYPATIFTTAPLENVQAAIKVAEK 242
            LL++PT Q + +D V+ G  V++EKDR LE F  +A  +C  L + GHW D+IDPCSGLPM+      PY+EV G   LL Y T NAGCCK++LHP+WG+S YPAT+F  AP E +QAAIK AE+
Sbjct:   17 LLVVPTCQHATLDLVKTGEAVDDEKDRLLERFMKWAVAVCARLLAAGHWCDYIDPCSGLPMIHQESQTPYSEVEGLSLLLGYKTANAGCCKVVLHPKWGTSVYPATLFARAPFEALQAAIKGAEE 141          
BLAST of NO22G01110 vs. NCBI_GenBank
Match: GAX79736.1 (hypothetical protein CEUSTIGMA_g7177.t1 [Chlamydomonas eustigma])

HSP 1 Score: 151.8 bits (382), Expect = 3.100e-33
Identity = 74/136 (54.41%), Postives = 94/136 (69.12%), Query Frame = 0
Query:  116 QLLILPTIQRSRVDTVRFGVDVEEEKDRCLEYFADFARPLCESLRSQGHWADFIDPCSGLPMMTPHCTRPYNEVAGFEHLLRYTTQNAGCCKILLHPRWGSSCYPATIFTTAPLENVQAAIKVAEKGEA-WREGGI 251
            +LLI+PT QRS +D V+ G +V+ EKDR LE F  ++  +C+ L  QGHWADFIDPCSGL M+     + Y+EV     L  Y T NAGCCK+LLHP WGSS YPAT+FT APL+ + +AIK AE  EA  +E G+
Sbjct:   39 KLLIVPTCQRSVMDLVQTGEEVDVEKDRLLERFMVWSETVCKILSDQGHWADFIDPCSGLAMIHKDSQQVYSEVEALSVLKGYKTANAGCCKVLLHPHWGSSVYPATMFTCAPLDALLSAIKQAEVSEAVLKEAGL 174          
BLAST of NO22G01110 vs. NCBI_GenBank
Match: PRW60433.1 (ATP-dependent RNA helicase DDX1 [Chlorella sorokiniana])

HSP 1 Score: 150.2 bits (378), Expect = 8.900e-33
Identity = 65/114 (57.02%), Postives = 84/114 (73.68%), Query Frame = 0
Query:  117 LLILPTIQRSRVDTVRFGVDVEEEKDRCLEYFADFARPLCESLRSQGHWADFIDPCSGLPMMTPHCTRPYNEVAGFEHLLRYTTQNAGCCKILLHPRWGSSCYPATIFTTAPLE 231
            +L++PT Q++++D V+ G  VE+EKDR LE F +FA+ +CE L + GHWAD+IDPCSGLPM+       Y EV     LL Y TQNAGCCKI+LHP+WGSS YPA++F  APLE
Sbjct:   44 MLVIPTCQQAQMDLVQMGQKVEDEKDRLLERFVEFAKVVCERLAAAGHWADYIDPCSGLPMVHRGTNAVYGEVEALVTLLGYKTQNAGCCKIILHPKWGSSVYPASMFAKAPLE 157          
BLAST of NO22G01110 vs. NCBI_GenBank
Match: EJK47732.1 (hypothetical protein THAOC_33529 [Thalassiosira oceanica])

HSP 1 Score: 149.8 bits (377), Expect = 1.200e-32
Identity = 67/113 (59.29%), Postives = 83/113 (73.45%), Query Frame = 0
Query:  117 LLILPTIQRSRVDTVRFGVDVEEEKDRCLEYFADFARPLCESLRSQGHWADFIDPCSGLPMMTPHCTRPYNEVAGFEHLLRYTTQNAGCCKILLHPRWGSSCYPATIFTTAPL 230
            LL +PT QRSR D V  G  +E EKDR L  F DF + +CE++RS+G+WAD+IDPCSGLPM++ +C + Y+EV G E LL Y   NAG CKIL HPRWGS+ YPATIF  AP+
Sbjct:   67 LLAIPTNQRSREDLVAVGDHIEAEKDRLLNVFLDFGKFVCENIRSKGYWADYIDPCSGLPMISLNCNKVYSEVDGMECLLNYRAYNAGFCKILTHPRWGSAVYPATIFAYAPV 179          
BLAST of NO22G01110 vs. NCBI_GenBank
Match: XP_012199898.1 (hypothetical protein SPRG_05933 [Saprolegnia parasitica CBS 223.65] >KDO29396.1 hypothetical protein SPRG_05933 [Saprolegnia parasitica CBS 223.65])

HSP 1 Score: 149.8 bits (377), Expect = 1.200e-32
Identity = 76/200 (38.00%), Postives = 112/200 (56.00%), Query Frame = 0
Query:   37 PRLLMNGIELSIHTCTKSMAREVRYIFPHLSLNSNTGANRSGDKARVPAELHATITMPSTEIGVAGGLEKRRQDEERRGQLLILPTIQRSRVDTVRFGVDVEEEKDRCLEYFADFARPLCESLRSQGHWADFIDPCSGLPMMTPHCTRPYNEVAGFEHLLRYTTQNAGCCKILLHPRWGSSCYPATIFTTAPLENVQAAI 237
            P +  +G+E+S+H C +++ RE+ ++FP                        AT+   S  +GV                     T QR+ VD  +FG + ++EKDR LE FA +A+ +  ++ + GHWADFIDPCSGLPM+  + ++ Y+EV G E LL Y+  +AG CKILLHP WG++ YPA++FTTAP + V A I
Sbjct:   26 PTMTSSGLEVSVHECPRALLRELVHVFP------------------------ATLKKDSAVLGVV--------------------TCQRACVDLAQFGSEADKEKDRLLENFARWAQDVATAILASGHWADFIDPCSGLPMLAMNSSKVYSEVDGVEVLLHYSCLSAGMCKILLHPEWGAAVYPASLFTTAPYDVVHAII 181          
BLAST of NO22G01110 vs. NCBI_GenBank
Match: PNW85495.1 (hypothetical protein CHLRE_03g189200v5 [Chlamydomonas reinhardtii])

HSP 1 Score: 148.7 bits (374), Expect = 2.600e-32
Identity = 69/128 (53.91%), Postives = 88/128 (68.75%), Query Frame = 0
Query:  116 QLLILPTIQRSRVDTVRFGVDVEEEKDRCLEYFADFARPLCESLRSQGHWADFIDPCSGLPMMTPHCTRPYNEVAGFEHLLRYTTQNAGCCKILLHPRWGSSCYPATIFTTAPLENVQAAIKVAEKGE 244
            QLLI+PT Q + VD V  G  VE EKDR LE F  +A+ +C+ L + GHWAD+IDPCSGLPM+       Y EV+    L+ Y T NAGCCK+LLHP WGS+ YPA++FT APL+ + AAI+VA   +
Sbjct:   39 QLLIVPTCQHAIVDLVNTGERVEGEKDRLLERFMAWAKVVCDQLSTAGHWADYIDPCSGLPMIHTDLNVVYPEVSALSVLMGYQTSNAGCCKVLLHPAWGSAVYPASLFTEAPLDALLAAIQVANASQ 166          
The following BLAST results are available for this feature:
BLAST of NO22G01110 vs. NCBI_GenBank
Analysis Date: 2019-07-11 (BLASTP analysis of N. oceanica IMET1 genes)
Total hits: 20
Match NameE-valueIdentityDescription
XP_005853627.17.000e-5480.67hypothetical protein NGA_0430401 [Nannochloropsis ... [more]
GAQ88723.16.600e-3659.20hypothetical protein KFL_004540080 [Klebsormidium ... [more]
XP_005851808.14.700e-3456.10hypothetical protein CHLNCDRAFT_133264 [Chlorella ... [more]
PSC75053.11.100e-3349.66Methylmalonic aciduria and homocystinuria type D m... [more]
XP_013893335.11.800e-3354.40hypothetical protein MNEG_13646 [Monoraphidium neg... [more]
GAX79736.13.100e-3354.41hypothetical protein CEUSTIGMA_g7177.t1 [Chlamydom... [more]
PRW60433.18.900e-3357.02ATP-dependent RNA helicase DDX1 [Chlorella sorokin... [more]
EJK47732.11.200e-3259.29hypothetical protein THAOC_33529 [Thalassiosira oc... [more]
XP_012199898.11.200e-3238.00hypothetical protein SPRG_05933 [Saprolegnia paras... [more]
PNW85495.12.600e-3253.91hypothetical protein CHLRE_03g189200v5 [Chlamydomo... [more]

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Relationships

This gene is member of the following syntenic_region feature(s):

Feature NameUnique NameSpeciesType
nonsL033nonsL033Nannochloropsis oceanica (N. oceanica IMET1)syntenic_region
ncniR025ncniR025Nannochloropsis oceanica (N. oceanica IMET1)syntenic_region
ngnoR078ngnoR078Nannochloropsis oceanica (N. oceanica IMET1)syntenic_region
ngnoR077ngnoR077Nannochloropsis oceanica (N. oceanica IMET1)syntenic_region


This gene is orthologous to the following gene feature(s):

Feature NameUnique NameSpeciesType
NSK004149NSK004149Nannochloropsis salina (N. salina CCMP1776)gene


The following polypeptide feature(s) derives from this gene:

Feature NameUnique NameSpeciesType
NO22G01110.1NO22G01110.1-proteinNannochloropsis oceanica (N. oceanica IMET1)polypeptide


The following gene feature(s) are orthologous to this gene:

Feature NameUnique NameSpeciesType
Naga_100019g30gene8964Nannochloropsis gaditana (N. gaditana B-31)gene


The following mRNA feature(s) are a part of this gene:

Feature NameUnique NameSpeciesType
NO22G01110.1NO22G01110.1Nannochloropsis oceanica (N. oceanica IMET1)mRNA


Sequences
The following sequences are available for this feature:

gene sequence

>NO22G01110 ID=NO22G01110|Name=NO22G01110|organism=Nannochloropsis oceanica|type=gene|length=795bp
ATGACTGACGATATCTGCTGCTACCCTTCTGGTGTCACTGTCACCACCAC
CTCCACTGCCCCAGCAGCTGGCGCTGGAGTAGCCCAGCCAATGGGGATGG
TGGAAGCGCCCCGACTGCTGATGAATGGGATCGAGCTCTCCATCCATACC
TGCACTAAGTCCATGGCGAGAGAGGTCAGGTATATATTCCCTCACCTTTC
GTTGAACAGCAACACCGGTGCGAACCGCAGTGGAGACAAGGCTCGAGTGC
CGGCGGAGCTCCATGCTACGATTACAATGCCCAGCACTGAGATCGGCGTC
GCTGGCGGTCTGGAGAAGAGGCGACAGGACGAAGAAAGAAGAGGACAGCT
GCTCATCCTCCCCACCATTCAAAGGTCCCGGGTGGACACGGTGCGCTTCG
GCGTGGATGTGGAAGAAGAGAAAGACCGATGTCTCGAGTACTTCGCAGAT
TTCGCCCGCCCGCTTTGCGAAAGCTTGCGCAGCCAGGGCCACTGGGCGGA
TTTCATTGACCCTTGCTCGGGTCTGCCTATGATGACACCCCACTGCACTC
GACCCTACAATGAGGTCGCAGGCTTTGAACACTTACTTAGATACACAACA
CAGAACGCCGGGTGCTGCAAAATTTTGCTTCATCCCCGATGGGGCTCGAG
TTGTTATCCGGCTACAATTTTTACGACCGCCCCTCTTGAGAATGTCCAGG
CGGCTATCAAAGTGGCGGAGAAGGGGGAGGCATGGAGGGAGGGAGGGATT
GGAATGCGGCGTGTGATGGAGCCTGCGGGGGTTTTGGTGGATTGA
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protein sequence of NO22G01110.1

>NO22G01110.1-protein ID=NO22G01110.1-protein|Name=NO22G01110.1|organism=Nannochloropsis oceanica|type=polypeptide|length=265bp
MTDDICCYPSGVTVTTTSTAPAAGAGVAQPMGMVEAPRLLMNGIELSIHT
CTKSMAREVRYIFPHLSLNSNTGANRSGDKARVPAELHATITMPSTEIGV
AGGLEKRRQDEERRGQLLILPTIQRSRVDTVRFGVDVEEEKDRCLEYFAD
FARPLCESLRSQGHWADFIDPCSGLPMMTPHCTRPYNEVAGFEHLLRYTT
QNAGCCKILLHPRWGSSCYPATIFTTAPLENVQAAIKVAEKGEAWREGGI
GMRRVMEPAGVLVD*
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Synonyms
Publications