EWM20660.1, cds10008 (CDS) Nannochloropsis gaditana

BLAST of EWM20660.1 vs. NCBI_GenBank
Match: gi|585100465|gb|EWM20660.1| (Histidine phosphatase superfamily, clade-1 [Nannochloropsis gaditana])

HSP 1 Score: 891.723 bits (2303), Expect = 0.000e+0
Identity = 433/433 (100.00%), Postives = 433/433 (100.00%), Query Frame = 0

Query:    1 MYSNDISSNPDDCGGEALQGIGDGMRAMMDDPHGGTEVLFIRHAESRNNVLHAEVGARYNFDPNLHELMEKEVASLRSEDADLSEKGFVQAERLGEYLAERLRQRRVLVVTSPMQRAIKTIRPLVTRLGIGPEDFACYGRYFEVGGCYLQDRVYTGTSRAELEGTYKLQCFDVEEEGWYAHSKEREGHPQALLRCEQAWLWIQDVLLAGALPNAVDGDGRGGGRGGGRSYDTIVVVGHGEFMHYVMKKMVGGGSLSSALGFVHGNTGISTLQYHPSRGALVRSLNVLEHLPPSLRTGHALADGWWEVVPRPLSSSQRPLIHRFENLPEEEPGLHMATQAIRQRYLPPSLPPYLTDVDAHSVHFLALSHGQASVVGLALYDVRANRLRQVWKNREEGRGEWKKRTQTASSVPLRSLVFSVTLCFLLFLLPSFFR 433
            MYSNDISSNPDDCGGEALQGIGDGMRAMMDDPHGGTEVLFIRHAESRNNVLHAEVGARYNFDPNLHELMEKEVASLRSEDADLSEKGFVQAERLGEYLAERLRQRRVLVVTSPMQRAIKTIRPLVTRLGIGPEDFACYGRYFEVGGCYLQDRVYTGTSRAELEGTYKLQCFDVEEEGWYAHSKEREGHPQALLRCEQAWLWIQDVLLAGALPNAVDGDGRGGGRGGGRSYDTIVVVGHGEFMHYVMKKMVGGGSLSSALGFVHGNTGISTLQYHPSRGALVRSLNVLEHLPPSLRTGHALADGWWEVVPRPLSSSQRPLIHRFENLPEEEPGLHMATQAIRQRYLPPSLPPYLTDVDAHSVHFLALSHGQASVVGLALYDVRANRLRQVWKNREEGRGEWKKRTQTASSVPLRSLVFSVTLCFLLFLLPSFFR
Sbjct:    1 MYSNDISSNPDDCGGEALQGIGDGMRAMMDDPHGGTEVLFIRHAESRNNVLHAEVGARYNFDPNLHELMEKEVASLRSEDADLSEKGFVQAERLGEYLAERLRQRRVLVVTSPMQRAIKTIRPLVTRLGIGPEDFACYGRYFEVGGCYLQDRVYTGTSRAELEGTYKLQCFDVEEEGWYAHSKEREGHPQALLRCEQAWLWIQDVLLAGALPNAVDGDGRGGGRGGGRSYDTIVVVGHGEFMHYVMKKMVGGGSLSSALGFVHGNTGISTLQYHPSRGALVRSLNVLEHLPPSLRTGHALADGWWEVVPRPLSSSQRPLIHRFENLPEEEPGLHMATQAIRQRYLPPSLPPYLTDVDAHSVHFLALSHGQASVVGLALYDVRANRLRQVWKNREEGRGEWKKRTQTASSVPLRSLVFSVTLCFLLFLLPSFFR 433          

BLAST of EWM20660.1 vs. NCBI_GenBank
Match: gi|553192637|ref|XP_005855613.1| (nudix hydrolase [Nannochloropsis gaditana CCMP526] >gi|422293444|gb|EKU20744.1| nudix hydrolase [Nannochloropsis gaditana CCMP526])

HSP 1 Score: 481.871 bits (1239), Expect = 1.015e-162
Identity = 276/389 (70.95%), Postives = 286/389 (73.52%), Query Frame = 0

Query:    1 MYSNDISSNPDDCGGEALQGIGDGMRAMMDDPHGGTEVLFIRHAESRNNVLHAEVGARYNFDPNLHELMEKEVASLRSEDADLSEKGFVQAERLGEYLAERLRQRR--------------------------------------------------VLVVTSPMQRAIKTIRPLVTRLGIGPEDFACYGRYFEVGGCYLQDRVYTGTSRAELEGTYKLQ-------------CFDVEEEGWYAHS--------------------KEREGHPQALLRCEQAWLWIQDVLLAGALPNAVDGDGRGGGRGGGRSYDTIVVVGHGEFMHYVMKKMVGGGSLSSALGFVHGNTGISTLQYHPSRGALVRSLNVLEHLPPSLRTGHALADGWWE 306
            MYSND SSNPDDCGGEALQGIGDGMRAMMDDPHGGTEVLFIRHAESRNNVLHAEVGARYNFDPNLHELMEKEVASLRSEDADLSEKGFVQAERLGEYLAERLRQRR                                                  VLVVTSPMQRAIKTIRPLVTRLGIGPEDFACYGRYFEVGGCYLQDRVYTGTSRAELEGTYK++             CFDVEEEGWYAHS                    KEREGHPQALLRCEQAWLWIQDVLLAGALPNAVDGDGRGGGRGGGRSYDTIVVVGHGEFMHYVMKKM+GGGSLSSALGFVHGNTGISTLQ    R  + R+++V  H P +      L+ G +E
Sbjct:  229 MYSNDTSSNPDDCGGEALQGIGDGMRAMMDDPHGGTEVLFIRHAESRNNVLHAEVGARYNFDPNLHELMEKEVASLRSEDADLSEKGFVQAERLGEYLAERLRQRRLITQSNDEYVIVLLLASIPLLPPYESPTDATLTDDRHVSTSLSPPLTRHRVLVVTSPMQRAIKTIRPLVTRLGIGPEDFACYGRYFEVGGCYLQDRVYTGTSRAELEGTYKVKMERGECLEAGGRRCFDVEEEGWYAHSVRDFFLLSSPSSLFLPFPLQKEREGHPQALLRCEQAWLWIQDVLLAGALPNAVDGDGRGGGRGGGRSYDTIVVVGHGEFMHYVMKKMIGGGSLSSALGFVHGNTGISTLQ----RPLIHRTISV--HTPWARMKAFYLSRGGFE 611          

BLAST of EWM20660.1 vs. NCBI_GenBank
Match: gi|747217087|gb|KIG16636.1| (hypothetical protein DB30_04255 [Enhygromyxa salina])

HSP 1 Score: 159.458 bits (402), Expect = 2.289e-42
Identity = 94/268 (35.07%), Postives = 141/268 (52.61%), Query Frame = 0

Query:   38 VLFIRHAESRNNVLHAEVGARYNFDPNLHELMEKEVASLRSEDADLSEKGFVQAERLGEYLAERLRQRRVLVVTSPMQRAIKTIRPLVTRLGIGPEDFACYGRYFEVGGCYLQDRVYTGTSRAELEGTYKLQCFDVEEEGWYAHSKEREGHPQALLRCEQAWLWIQDVLLAGALPNAVDGDGRGGGRGGGRSYDTIVVVGHGEFMHYVMKKMVGGGSLSSALGFVHGNTGISTLQYHPSRGALVRSLNVLEHLPPSLRTGHALADGWW 305
            +L +RHA+S NN+ +A +  ++  DP   E M+ E    R  D +L+E G  QA  L + LA  L   R L+V+SPM+RA++T      R GI  + F C G  FEVGGC+  D     ++ A++E  + + C ++  EGWY      E   +   R ++   W   +L +G                    +DTIVVV HG+ +   +++ +   + S  L FVHGNTG++TL + PS G L+  LN +EHLP  LRTG A ++ WW
Sbjct:    4 LLLVRHAQSENNLSNARIREQFRSDP---ERMQLEANRARQADPELTETGREQASLLAKTLAPILASSRSLLVSSPMRRALRTAAASAERAGI--DRFTCEGELFEVGGCHYCDEARPSSTTAQIEAEFPVACRNIGPEGWYGGRAVSERANEVSARVDRVITWANTILASG-------------------DHDTIVVVTHGDLLSRWLRRWLHVPA-SRGLAFVHGNTGVTTLSWDPSDGLLLEGLNAVEHLPAPLRTG-ADSEFWW 245          

BLAST of EWM20660.1 vs. NCBI_GenBank
Match: gi|551569388|ref|XP_005770649.1| (hypothetical protein EMIHUDRAFT_196356 [Emiliania huxleyi CCMP1516] >gi|485621777|gb|EOD18220.1| hypothetical protein EMIHUDRAFT_196356 [Emiliania huxleyi CCMP1516])

HSP 1 Score: 150.984 bits (380), Expect = 2.276e-37
Identity = 125/373 (33.51%), Postives = 175/373 (46.92%), Query Frame = 0

Query:   40 FIRHAESRNNVLHAEV------GARYNFDPNLHELMEKEVASLRSEDADLSEKGFVQAERLGEYLA-ERLRQRRVLVVTSPMQRAIKTIRPLVTRL---GIGPEDFACYGRYFEVGGCYLQDRVYTGTSRAELEGTYKL-----QCFDVEEEGWYAHSKEREGHPQALLRCEQAWLWIQDVLLAGALPNAVDGDGRGGGRGGGRSYDTIVVVGHGEFMHYVMKKMVGGGSLSSALGFVHGNTGISTLQYHPSRGA-LVRSLNVLEHLPPSLRTG-HALADGWWEVVPRPLSSSQR--PLIHRFENLPEEEPGLHMATQAIRQRYL----PPSLPPYLTDVDAHSVHFLALSHGQASVVGLALYDVRANRLRQV 389
             +RHAES NN L+ E+       A    DP+L   +++E A  RS D  LS +G  QA R+GE+LA E L     L+V SPM+RA+ T  P+   L   G+      C+ +YFE GGC+   R   G +  ++ G + L     +CF   + GWY+ +   E   Q   R E+  LWI + L   ALP+     GR            +++VGHG FM  ++ ++VG     +A  FVH NTG+STL+    +G+ LV  LN   HL P L TG H   DGW   +  P    +R  P       +P    GL       R+R L             + DA SV F+ +  G  +  G   YD    RLRQ+
Sbjct:    6 LVRHAESANNALYNEIISECGGAAAVASDPSLQRRVDEEEARRRSSDPPLSARGLEQAARVGEHLAGENLDCASTLLVCSPMRRALLTAAPIARGLKGAGVANLRVECHAQYFEAGGCHEGGRALPGRTFQQICGDHPLDFDAAECFPSPDRGWYSAAGAPESDAQP--RAERMCLWITERL--AALPD----TGR------------VIMVGHGAFMARLLARLVGLPCAGAAALFVHANTGVSTLRLVRRKGSFLVLGLNQTPHLTPQLLTGAHPAEDGWAAALRAPAWVVRRYGPEAVGCYPMPT---GLRRQLLEARRRLLWAHESGVGASAYEESDARSVTFVCVLEGSETPAGQVQYDPSTRRLRQM 355          

BLAST of EWM20660.1 vs. NCBI_GenBank
Match: gi|494032368|ref|WP_006974505.1| (putative phosphoglycerate mutase/fructose-2,6-bisphosphatase [Plesiocystis pacifica] >gi|149816842|gb|EDM76330.1| putative phosphoglycerate mutase/fructose-2,6-bisphosphatase [Plesiocystis pacifica SIR-1])

HSP 1 Score: 117.087 bits (292), Expect = 2.908e-25
Identity = 106/354 (29.94%), Postives = 159/354 (44.92%), Query Frame = 0

Query:   38 VLFIRHAESRNNVLHAEVGARYNFD----PNLHELMEKEVASLRSEDADLSEKGFVQAERLGEYLAERLRQRRVLVVTSPMQRAIKTIRPLVTRLGIGPEDFACYGRYFEVGGCYLQDRVYTGTSRAELEGTYKLQCFDVEEEGWYA----HSKEREGHPQALLRCEQAWLWIQDVLLAGALPNAVDGDGRGGGRGGGRSYDTIVVVGHGEFMHYVMKKMVGGGSLSSALGFVHGNTGISTLQY---HPSRGALVRSLNVLEHLPPSLRTGHALADGWWEVVPRPLSSSQRPLIHRFENLPEEEPGLHMATQAIRQRYLPPSLPPYLTDVDAHSVHFLALSHGQASVVGLALYD 380
            +L +RHA+S+NNV HA+     + D     +L+E       + R+ D +LS  G  QA  +GE L     +   L+V SPM+RA+ T + +     +  E F C G  +EVGG Y+ +R     +   LE  + + C D+ E GWY+     S+  E       R ++   W Q +                G     R +   +VV HG+ M   ++++        +  FVHGNTGI+ +Q     P  GAL+++ N LEHLP +LR+G  L   WW      +  S   L    E +PE   G   A  + R           L  + A SV  +A   G+  VVG AL+D
Sbjct:   12 LLLVRHAQSQNNVAHAQSVEDCDGDLVRAKDLYE-------TRRAADPELSALGRRQAAIVGEALGPLAARPDTLLVASPMRRALDTAQAIAEVGQVPRERFRCQGDLYEVGGAYVGERAAATANADALEAAHPVHCRDISEAGWYSGRGVESRGAEPVEHCWARLDRVMAWTQAL----------------GAEAMERGWSRAIVVVHGDLMSRWLRRLFEVPWYQRS-AFVHGNTGITRVQLALGDPGGGALLQAHNELEHLPAALRSG--LGPVWWHYSWPDVEVS---LHDTLEAVPEAWRGALEALWSARGFGPDVESLDALGPIAARSVWCVARVRGE--VVGGALHD 334          

BLAST of EWM20660.1 vs. NCBI_GenBank
Match: gi|1210513604|dbj|GAX27476.1| (hypothetical protein FisN_23Hh059 [Fistulifera solaris])

HSP 1 Score: 110.923 bits (276), Expect = 1.982e-23
Identity = 100/326 (30.67%), Postives = 147/326 (45.09%), Query Frame = 0

Query:   38 VLFIRHAESRNNVLHAE---VGARYNFDPNLHELMEKEVASLRSEDADLSEKGFVQAERLGEYLAERLRQRRVLVVTSPMQRAIKTIRPLVTRLGIGPEDFACYGRYFEVGGCYLQDRVYTGTSRAELEGTYKLQCFDVE-----EEGWYAHSKEREGHPQALLRCEQAWLWIQDVL---LAGALPNAVDGDGRGGGRGGGRSYDTIVVVGHGEFMHYVMKKMVGG-GSLSSALG------FVHGNTGISTLQYHPSRGALVRSLNVLEHLPPS-LRTGHALADGWWEVVPRPLSSSQRPLIHRFENLPEEEPGLHMATQAIRQRY 344
            +  IRHAES NN ++ E   + A  N         +  V S R  D  LS+ G  QAE LGEYL      R   ++TSPM+R + TIRP++      P     +G YFE  GC+L+D+   G   +E++   +    D         GWY + K  E    +  R  + ++W  + L   LA      +D D              I  VGHG+FM  V+K++V   G  +   G      FVH NT ++ L+Y      LV   NV+ H+P + L +G  L DGW  ++P    ++   ++    N  E EP +   TQA+   Y
Sbjct:   14 IRLIRHAESYNNQVYREARQLPASAN--------RQAYVDSNRLADPGLSDLGHQQAELLGEYL------RPTQILTSPMKRTLTTIRPILKNHPTCP--VLVHGLYFESEGCHLKDQPMEGMKPSEIKEYLQHDNVDFTGFPDMNRGWYCNEKGPETRESSEGRATRFYMWFCNYLDEQLA-----LMDHDKEKTANA------LIACVGHGDFMSLVLKRIVASYGHATERTGTTHRSSFVHSNTAMTHLEYFGYGRFLVLQQNVVPHIPDAKLWSGGTLKDGWSYLIPDVAETTVAVIL----NEEEMEPYIREQTQALEALY 308          

BLAST of EWM20660.1 vs. NCBI_GenBank
Match: gi|1210514574|dbj|GAX26531.1| (hypothetical protein FisN_23Lh059 [Fistulifera solaris])

HSP 1 Score: 105.531 bits (262), Expect = 1.627e-21
Identity = 92/320 (28.75%), Postives = 142/320 (44.38%), Query Frame = 0

Query:   38 VLFIRHAESRNNVLHAEVGARYNFDPNLHELMEKEVASLRSEDADLSEKGFVQAERLGEYLAERLRQRRVLVVTSPMQRAIKTIRPLVTRLGIGPEDFACYGRYFEVGGCYLQDRVYTGTSRAELEGTYK-----LQCFDVEEEGWYAHSKEREGHPQALLRCEQAWLWIQDVLLAGALPNAVDGDGRGGGRGGGRSYDTIVVVGHGEFMHYVMKKMVGG-GSLSSALG------FVHGNTGISTLQYHPSRGALVRSLNVLEHLPPS-LRTGHALADGWWEVVPRPLSSSQRPLIHRFENLPEEEPGLHMATQAIRQRY 344
            +  +RHAES NN ++ E   +     N     +  V   R  D  LS+ G+ QAE LGEYL      +   ++TSPM+R + TI+P++      P     +G YFE  GC+L+D+   G   +E++   +        F     GWY   K  E    +  R  + ++W  + L         D +              I  VGHG+FM  V+K++V   G  +   G      FVH NT ++ L+Y      LV   NV+ H+P S L +G  L DGW  ++P    ++   ++    N  + EP +   TQA+   Y
Sbjct:   14 IRLVRHAESYNNQVYRE-ARQLPVSAN----RQAYVDCNRLADPGLSDLGYRQAELLGEYL------QPTQILTSPMKRTLSTIQPILKHHPTCP--VLVHGFYFESEGCHLKDQPMEGMKPSEIKDYLQHDHVEFTGFPDMNRGWYCDEKGPETRESSEERATRFYMWFCNYLDEQLAFMNHDKEKTENA--------LIACVGHGDFMSLVLKRIVASYGHTTERTGTTHRSSFVHSNTAMTHLEYFGYGRFLVLQQNVVPHIPDSNLLSGGTLKDGWSYLIPDVAETTVAVIL----NEKQMEPYIREQTQALEALY 308          

BLAST of EWM20660.1 vs. NCBI_GenBank
Match: gi|551578508|ref|XP_005774842.1| (hypothetical protein EMIHUDRAFT_255102, partial [Emiliania huxleyi CCMP1516] >gi|485626726|gb|EOD22413.1| hypothetical protein EMIHUDRAFT_255102, partial [Emiliania huxleyi CCMP1516])

HSP 1 Score: 100.908 bits (250), Expect = 2.557e-21
Identity = 68/189 (35.98%), Postives = 97/189 (51.32%), Query Frame = 0

Query:   40 FIRHAESRNNVLHAEV------GARYNFDPNLHELMEKEVASLRSEDADLSEKGFVQAERLGEYLA-ERLRQRRVLVVTSPMQRAIKTIRPLVTRL---GIGPEDFACYGRYFEVGGCYLQDRVYTGTSRAELEGTYKL-----QCFDVEEEGWYAHSKEREGHPQALLRCEQAWLWIQDVLLAGALPN 213
             +RHAES NN L+ E+       A    DP+L   +++E A  RS D  LS +G  QA R+GE+LA E L     L+V SPM+RA+ T  P+   L   G+      C+ +YFE GGC+   R   G +  ++ G + L     +CF   + GWY+ +   E   Q   R E+  LWI + L   ALP+
Sbjct:    6 LVRHAESANNALYNEIISECGGAAAVASDPSLQRRVDEEEARRRSSDPPLSARGLEQAARVGEHLAGENLDCASTLLVCSPMRRALLTAAPIARGLKGAGVANLRVECHAQYFEAGGCHEGGRALPGRTFQQICGDHPLDFDAAECFPSPDRGWYSAAGAPESDAQP--RAERMCLWITERL--AALPD 190          

BLAST of EWM20660.1 vs. NCBI_GenBank
Match: gi|223992939|ref|XP_002286153.1| (predicted protein [Thalassiosira pseudonana CCMP1335] >gi|220977468|gb|EED95794.1| predicted protein [Thalassiosira pseudonana CCMP1335])

HSP 1 Score: 99.3673 bits (246), Expect = 1.272e-19
Identity = 93/319 (29.15%), Postives = 140/319 (43.89%), Query Frame = 0

Query:   34 GGTEVLFIRHAESRNNVLHAEVGARYNF---DPNLHELMEKEVASLRSEDADLSEKGFVQAERLGEYLAERLRQRR---VLVVTSPMQRAIKTIRPLVTRLGIGPE-----DFACYGRYFEVGGCYLQDRVYTGTSRAELEGTYKLQCFDVE--------EEGWYAHSKEREGHPQALLRCEQAWLWIQ----------------DVLLAG-ALPNAVDGDGRGGGRGGGRSYDTIVVVGHGEFMHYVMKKMVGG-------GSLSSALGFVHGNTGISTLQYHPSRGALVRSLNVLEHLPPS-LRTGHALADGWWEVV 308
            GG     ++  +S+NN ++ +    Y     D +L   + K V   RS D  LS+ G  QAE L EYL   L  +    V  + SPM+R I+TI P +T L          D    G YFE  GC+ +++V  G +  +++        +          E+GWYAH+   E   ++  R  + +LW+                 DV  AG  LP   D           R   T + +GHG+FM  V+K+++ G        ++     FVH NTGI+ L+Y  +   LV S N + HL  +   TG +L DGW  V+
Sbjct:    7 GGWVAAVVQTTKSQNNQVYRDARRIYKGGTPDFDLDGWL-KYVDDRRSADPGLSDNGKKQAELLAEYLEPHLLNQASTPVKFIVSPMKRTIETILPTLTALNRDSYRENSCDVIINGLYFESEGCHTREQVEPGMNANDIQSLLAPSGVNASFTGFQRGVEKGWYAHATGPETRQESEERAAKFYLWLVEHLDQQLYEAEEQDAVDVFDAGVTLPEEEDEQDHDRFAPRNRRRRTAICIGHGDFMSLVLKRIIAGLGHAVERDTVPHRSAFVHFNTGITELEYFGNGRFLVMSSNQVPHLAGTEYITGGSLKDGWSYVI 324          

BLAST of EWM20660.1 vs. NCBI_GenBank
Match: gi|219122601|ref|XP_002181630.1| (predicted protein [Phaeodactylum tricornutum CCAP 1055/1] >gi|217406906|gb|EEC46844.1| predicted protein [Phaeodactylum tricornutum CCAP 1055/1])

HSP 1 Score: 100.523 bits (249), Expect = 3.026e-19
Identity = 111/428 (25.93%), Postives = 171/428 (39.95%), Query Frame = 0

Query:   38 VLFIRHAESRNNVLHAEVGARY-----NFDPNLHELMEKEVASLRSEDADLSEK-GFVQAERLGEYLAERLRQ---RRVLVVTSPMQRAIKTIRPLVTRLGI---GPEDFACYGRYFEVGGCYLQDRVYTGTSRAELEGTYK------------------------LQCFDVEEEGWYAHSKEREGHPQALLRCEQAWLWIQDVLLAGALPNAVDGDGRGGGRGGGRSYDTIVVV-------------------------GHGEFMHYVMKKMVGG-------GSLSSALGFVHGNTGISTLQYHPSRGALVRSLNVLEHL--PPSLRTGHALADGWWEVVPRPLSSSQRPLIHRFENLPEEEPGLHMATQAIRQRYL---PPSLPPYLTD---VDAHSVHFLALSHGQASVVGLALYDVRANRLRQV 389
            V +IRHAESRNN ++ +   RY     +FD    +  +  V + R+ D  LS+  G  QA+ L +YL     +   R V +V SPM+R + T RP   R+ +   G      +G  FE  GC+ +     G S  E+   ++                           F   + GWY H +  E    +  R  + +LW+ + L    L +A D D     +     +D  V +                         GHG+FM  V+K++V G         +     F H NTG++ L+Y      LV + N + HL   P L +G +L DGW  ++P         +   F +  E EP +H   QA+R  Y    P +   ++ D    D  +V    +  G   VVG+A +     RL  V
Sbjct:   25 VRWIRHAESRNNQVYRDARVRYGGGTPDFDV---QGWQTYVDTHRTADPGLSDPCGNAQADCLADYLVPHWTEQASRPVRIVVSPMRRTLDTFRPTCQRMELANPGSTQVLVHGFLFESEGCHDRGLPREGDSPLEIAERWQATDDHDDNNKHNNSNDNTPSQPLDFTGFPDPDRGWYVHGQGPETRAASEQRAAKFYLWLNEYLDQQLLESANDNDTEQPQQQHHDVFDAGVAIPGEEDEVDHDKFAPRVRRRRTVVLVGHGDFMSLVLKRIVAGYGHYVENDGIPHRSAFCHYNTGMTELEYFGHGRFLVMTHNTVPHLQNTPELLSGGSLKDGWSYLMPNDQFVLDAEVNVAFAD--ELEPHIHEQAQALRALYRSDHPLAGNTFIHDDGTADNDTVTHFVVQRG-LQVVGVATHSAATGRLTDV 446